Namuhla, sithole umbuzo othakazelisayo ovela ku-Velentium Medical, inkampani ebuza ngokutholakala kwethu kwezintambo zikamazibuthe ezihambisana ne-biocompatible kanye nezintambo ze-Litz, ikakhulukazi lezo ezenziwe ngesiliva noma igolide, noma ezinye izixazululo zokufaka umswakama ezihambisana ne-biocompatible. Lesi sidingo sihlobene nobuchwepheshe bokushaja okungenantambo kwamadivayisi ezokwelapha afakwayo.
I-Tianjin Ruiyuan Electrical Equipment Co., Ltd. ike yahlangabezana nemibuzo enjalo ngaphambili futhi inikeze amakhasimende izixazululo ezisezingeni eliphezulu. I-Ruiyuan Laboratory iphinde yenza ucwaningo olulandelayo ngegolide, isiliva, kanye nethusi njengezinto ezifakwa emzimbeni:
Kumadivayisi ezokwelapha afakwa emzimbeni, ukuhambisana kwezinto eziphilayo kuncike ekusebenzisaneni kwazo nezicubu zomuntu, okuhlanganisa izici ezifana nokumelana nokugqwala, impendulo yokuzivikela komzimba, kanye nobuthi obuvela ku-cytotoxicity. Igolide (Au) nesiliva (Ag) ngokuvamile kubhekwa njengokuhambisana okuhle kwezinto eziphilayo, kuyilapho ithusi (Cu) lihambisana kabi nezinto eziphilayo, ngenxa yezizathu ezilandelayo:
1. Ukuhambisana kweGolide (Au)
Ukungasebenzi kahle kwamakhemikhali: Igolide liyinsimbi enhle engakwazi ukugqwala noma ukugqwala endaweni yemvelo futhi ayikhiphi inani elikhulu lama-ion emzimbeni.
Ukuqina okuphansi kwamasosha omzimba: Igolide alivamile ukubangela ukuvuvukala noma ukwenqatshwa kwamasosha omzimba, okwenza lifaneleke ukufakwa isikhathi eside.
2. Ukuhambisana kwesiliva (Ag)
Impahla yokulwa namagciwane: Ama-ion esiliva (i-Ag⁺) anemiphumela yokulwa namagciwane ebanzi, ngakho-ke asetshenziswa kabanzi ezifakelweni zesikhashana (njenge-catheter kanye ne-wound dressing).
Ukukhishwa okulawulwayo: Nakuba isiliva lizokhipha inani elincane lama-ion, ukwakheka okunengqondo (njengokumbozwa kwe-nano-silver) kunganciphisa ubuthi, kube nemiphumela yokulwa namagciwane ngaphandle kokulimaza kakhulu amangqamuzana abantu.
Ubuthi obungaba khona: Ukugxila okuphezulu kwama-ion esiliva kungabangela ubuthi obuvela ku-cytotoxicity, ngakho-ke kuyadingeka ukulawula ngokucophelela umthamo kanye nezinga lokukhululwa.
3. Ukuhambisana kwe-Biocompatibility kwe-Copper (Cu)
Ukusabela kwamakhemikhali okuphezulu: Ithusi likhishwa kalula endaweni yoketshezi lomzimba (njengokwakha i-Cu²⁺), futhi ama-ion ethusi akhishwe azobangela ukusabela kwama-free radical, okuholela ekulimaleni kwamangqamuzana, ukuphuka kwe-DNA, kanye nokuguquka kwamaprotheni.
Umphumela wokuvuvukala: Ama-ion ethusi angavuselela isimiso somzimba sokuzivikela, okubangela ukuvuvukala okungapheli noma i-tissue fibrosis.
Ubuthi be-Neuro: Ukuqongelela kakhulu kwethusi (njengesifo sikaWilson) kungalimaza isibindi kanye nesistimu yezinzwa, ngakho-ke akufaneleki ukufakwa isikhathi eside.
Ukusetshenziswa Okungavamile: Impahla yethusi yokulwa namagciwane ivumela ukuthi isetshenziswe kumadivayisi ezokwelapha esikhashana (njengezinto zokugqoka ezilwa namagciwane), kodwa inani lokukhululwa kumele lilawulwe ngokuqinile.
Isifinyezo Esiyinhloko
| Izici | Igolide(I-1965)AU） | Isiliva (Ag) | Ithusi (Cu) |
| Ukumelana nokugqwala | Kunamandla kakhulu (okungaqinile) | Okumaphakathi (Ukukhishwa kancane kwe-Ag+) | Kubuthakathaka (Ukukhishwa okulula kwe-Cu²+) |
| Impendulo yomzimba | Cishe akukho lutho | Iphansi (Isikhathi esilawulekayo) | Okuphezulu (Okubangela ukuvuvukala) |
| Ubuthi be-Ctotoxicity | Akukho | Okuphakathi nendawo (Kuya ngokuthi ugxile kangakanani) | Phezulu |
| Ukusetshenziswa okuyinhloko | Ama-electrode/ama-prostheses afakwe isikhathi eside | Ukufakelwa kwesikhashana okulwa namagciwane | Okungavamile (Kudinga ukwelashwa okukhethekile) |
Isiphetho
Igolide nesiliva kuyathandwa kakhulu ezintweni zokufakelwa kwezokwelapha ngenxa yokungagqwali kwazo okuphansi kanye nemiphumela yazo elawulwayo yezinto eziphilayo, kuyilapho umsebenzi wamakhemikhali wethusi kanye nobuthi bukhawulela ukusetshenziswa kwayo ezifakweni zesikhathi eside. Kodwa-ke, ngokuguqulwa kwendawo (njengokumbozwa kwe-oxide noma ukuhlanganiswa), impahla yethusi yokulwa namagciwane ingasetshenziswa ngezinga elilinganiselwe, kodwa ukuphepha kumele kuhlolwe ngokucophelela.
Isikhathi sokuthunyelwe: Julayi-18-2025
